La semana pasada nos visitaron un grupo de alumnos y profesores de Nottingham University. Dentro de sus programas de Doctorado de Ciencias, prepararon una serie de talleres y charlas formativas relacionados con la Biotecnología, a los que asistieron los alumnos de 4º de ESO. Aislamiento de ADN, reconocimiento de proteínas, acción de enzimas, virus y bacterias, fueron algunos de los temas tratados. Nuestros alumnos se desenvolvieron perfectamente con los invitados ingleses, y quedamos emplazados para futuras colaboraciones.
The presentation will discuss background of DNA, advances in sequencing (first, second, third generation), basic background into virus structure, and applications of Nanopore sequencing (minION) in West Africa for rapid identification of individuals with the Ebola virus.
The activity/ demonstration will involve extraction of DNA from a banana. During the waiting period in the experiment we will do an interactive question and answer session on basic virus structure using a model of a T4 phage.
The outer casing of a minION sequencer with a dummy flowcell will be passed around as a prop.
2) Synthetic Biology/ Bacterial engineering
The presentation will introduce the concept of and synthetic biology behind engineering of micro-organisms. It will emphasise the use of Genetically Modified Organisms (GMOs) in the industry and how GMOs can be used to solve specific problems. It will then focus on breaking down the «toolbox» that is available to the molecular engineer and applying it to example problems, showcasing approaches to increasingly difficult problems.
The activity will be an interactive paper-based session to address similar problems and to check understanding of principles discussed by construction of model answers.
3) Enzyme design and chirality
The presentation will introduce (or possibly extend) the background behind enzyme structure and function, looking particular at rational enzyme design of active sites for specific substrates. It will be made relatable by discussion of everyday use of the different enzymes in detergents to break down specific types of stain (sugars, fats, protein, etc.).
The activity will be an interactive demonstration of an enzymatic reaction either involving pineapples and amylase or potatoes and catalase (hydrogen peroxide reaction).
marzo 7, 2017